Rosai dorfman disease in child

Rosai dorfman disease in child

Rosai Dorfman disease, also known as sinus histiocytosis with massive lymphadenopathy, is a benign histiocytic proliferative condition of unsubstantiated etiology that most often presents as bilateral painless cervical lymphadenopathy.

The neck lymph nodes are the most frequently involved, followed by inguinal, axillary and mediastinal lymph nodes. The most common extranodal sites are the skin, the upper respiratory tract and bones. The skin is commonly affected; half of these patients have another associated extranodal site. Orbit and ocular glove involvement have been reported, usually as a retroorbitary mass and proptosis. The characteristic histological feature is lymphophagocytosis which is specific for this ...


Источник: “http://www.mif-ua.com/archive/article/39338”

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